Lose Weight: The Greater The Weight Loss Efficacy Of Possible Side Effects
By drugs Lose weight Certainly double-edged sword. To as Advertisement Called “effective” “security,” “no bounce” the weight loss drug, has not yet been developed.
Weight loss drugs, as with any other drugs are in the balance between necessity and side effects.
Greater weight loss efficacy of possible side effects
Obesity is being treated as a disease, and whether to use drugs to lose weight need to comply with medical advice. In general, only the BMI (“body mass index”, that is weight (in kilograms as a unit) divided by height (in meters) by the square of the value) is greater than 30, or greater than 27 and accompanied by other diseases (such as high blood pressure, high cholesterol, diabetes, etc.), doctors will recommend medication to lose weight. For the average overweight, use of drugs to lose weight is not considered necessary, or, more harm than good.
BMI and the relationship between body mass and disease risk in different populations due to rounding. Asians, BMI is generally lower than Europe and the United States. In China, that the BMI in the 18.5 to 23.9 is a reasonable value, from 24 to 27.9 is overweight, and above 28 is obese.
Lose weight or maintain a reasonable weight for health is very important, but weight loss drugs is undoubtedly through the double-edged sword. Advertising can be described as “effective” and “safety” “no bounce” the weight loss drug, has not yet been developed. Many to “beautiful” and people who lose weight, BMI value is far from the point of recommended drugs. From a health point of view, reasonable and healthy diet plus moderate exercise, is the most favorable.
Medicine may inhibit the absorption of fat liver injury
2009 8 24, United States Food Drug Administration (FDA) announced on popular weight loss drug Alai (Alli) and Xenical (Xenical) to investigate side effects. Over the past few years, FDA has received 32 cases of Allais or Xenical users report of liver injury.
Alai (Alli) are the only FDA approved non-prescription weight loss drug, people are free to buy. The prescription version of Xenical is Allais, twice the active ingredient is Alai, a doctor’s prescription to purchase. Xenical
Alai and Alai manufacturers refused to recognize the causes liver damage, the security they claim Alene has been a number of clinical trials support a hundred. The FDA has not yet determined directly related to liver damage and weight loss that can continue to take under the guidance of a doctor. However, Allais and questioned the safety of Xenical is far from stopped. Earlier this year, the British also began an investigation of its side effects.
Alai and the active ingredient in Xenical is called “Orlistat is (orlistat)”, is a lipase inhibitor. It is by interfering with fat digestion and inhibit fat absorption to reduce calorie intake to achieve weight loss. Scientific papers in taking 6 to 12 months, lost 2.9 kg were reported. However, while inhibiting fat absorption, fat-soluble vitamins (eg vitamin A, D, E, K, etc.) while the absorption also suppressed common side effects Diarrhea, flatulence, irregular bowel movements, abdominal pain and indigestion, etc. .
As a drug, orlistat weight loss it is obvious. Compared the efficacy of these side effects mentioned above also can be accepted. However, if the investigation confirmed that it will also damage the liver, then the side effects are too big.
Appetite control medicines can not be long-term consumption
There is a class of epinephrine to suppress appetite by changing the weight loss drug. One of the most commonly used is the phentermine (phentermine). Phentermine clear short-term weight loss, combined with appropriate lifestyle control, can lose an average of 3.6 kg. It is the most common side effects are dry mouth, headache, insomnia, nervousness, irritability, and constipation and so on. On the one hand, these side effects limit its long-term use of; the other hand, long-term use will lead to increased tolerance of the body, the effect on the decrease, and prone to dependence and abuse. PPA is the type of drugs, has been approved for sale as a non-prescription drugs, and later found that it may lead to hemorrhagic stroke woman, was canceled.
There is a class of diet pills with serotonin in vivo. They affect food intake over time, increasing the body’s basic metabolism, by “eating less”, “to consume” to achieve weight loss. FDA has approved fenfluramine (fenfluramine, Pondimin) and dexfenfluramine (dexfenfluramine, Redux) use, but because they have led to heart valve disease and pulmonary hypertension risk, manufacturers voluntarily withdrew in 1997, two products.
FDA also approved the use of a drug called sibutramine for weight loss. It has to change the adrenaline and the dual role of serotonin, weight loss more noticeable. 12 months after medication, there is subtracted from 4.2 to 4.5 kg were reported. Another previous study also reported that after two years to maintain the effect of lost 4 kg. However, it also can cause dry mouth, constipation, insomnia or high blood pressure and heart rate, and heart palpitations, etc. hyperthyroidism.
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