Chemically similar to the United States to fish "for" brain
According to the American physicist organization network on May 4 (Beijing time), U.S. scientists announced by the chemical treatment, one fish in the embryonic state of the brain can grow into the brain of fish close relatives. The study also found that the current widely accepted on brain evolution, "after a large (Lateequalslarge)" theory did not apply to fish. Research papers published in the May 3 issue of "U.S. National Academy of Sciences" on.
The mid 90s of last century, scientists study the evolution of the brain "after big" theory. They believe that the brain is only a piece of white board at first, as progenitor cells mature into nerve cells, nerve began to form, precursor cells into mature nerve cells in the later time, the greater the brain.
However, the U.S. Department of Biology, Georgia Institute of Technology Assistant Professor Todd? Slovak research team led by hanging Germain Lake Malawi in Africa in the six kinds of spine fin type of tropical fish at the pattern of brain development found that as early as fertilization 48 hours later, that is, before the process of neurogenesis, these differences in the brain of fish already there.
This six kinds of fish genome is almost the same, but its appearance and behavior are very different, of which three kinds of fish sojourn in the rock; the other three kinds of fish sojourn in the sand. Chui-Germain team from Sri Lanka ecology, genomics and developmental science and other aspects, the evolution of organisms to reveal the mystery out of this colorful form.
The research team in fish fertilization 2 days to 4 days repeated experiments, the results show that the sojourn in the sand in the fish, and the gene Wnt1 (Wnt family member of the neural stem cell proliferation and differentiation of a certain effect , Wnt1a protein can promote neural stem cells into nerve cells) and expression is more prominent, and the hypothalamus (in the center of the brain, are important brain functions between the site) is greater.
Slovakia vertical Germain explains that sojourn in the sand in the fish using visual search plankton, so the brain are used to integrate visual signals; the stranger in the land of fish on the rocks by the algae living on rocks, its brain has a greater may be in order to better control the environment around the complex three-dimensional.
Slovakia vertical Germain said other similar type of tropical fish fin spine as close to the species did not support "after big" assumption of data.
Research team trying to change the chemical pattern of gene expression in embryonic brain development to change the mode. In the use of lithium chloride on embryo took 3 hours to 5 hours of treatment, researchers embryos into the water and fish samples at different developmental stages of extraction. Found that Wnt signaling by lithium chloride treatment will make more prominent. Processing results show that they successfully sojourn in the rock fish was transformed into the brains of embryos sojourn in the sand in the fish brain.
Slovakia vertical Germain said that in brain development and evolution of the process, the process of neurogenesis is very important. This study showed that differences between species, the time the brain is much earlier than people know before.
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