HIV Reservoirs And Strategies To Control Them

Reference Portal on HIV Reservoirs & Eradication Strategies is a web portal that is launched to find out HIV cure and HIV control. This website is regularly updated with news and knowledge on HIV Reservoirs. A group of researchers and scientists have joined the forces to promote research and education on HIV reservoir.

In 2010 several papers have been published confirming that the CNS is a most important HIV reservoir, even in patients with effectively controlled plasma viremia. The pathogenesis of HIV infection in the brain has its own distinctiveness, as lymphocytes are not the core reservoir cells. Brain damage is not the effect of direct HIV damage, but is mediated by a range of proteins, cytokines and toxins. It is considered that HIV infection in the brain is well controlled with a very slow progression. In spite of highly active antiviral therapies (HAART), HIV scholars and researchers have observed life-long HIV persistence as a result of the establishment early on of a unwavering HIV reservoir pool of latently infected cells. The latent HIV reservoir of cells is recognized from the earliest point of infection and even though the number of latent cells can be reduced if HAART is initiated early on. Studies have exposed that absolute HIV eradication could take many decades under conditions of perfect viral suppression.

Since the time, HIV virus was first discovered; researchers have been researching on new and more effective HIV eradication therapies in the hope of finding a HIV cure. Right now, despite antiretroviral therapies,HIV reservoirs of latent infected cells still remain in infected individuals. Due to this HIV persistence, life-long antiviral therapy is presently required to control HIV, but the ultimate endeavor is to achieve long-term drug-free remission in those who have been infected and to develop a HIV prophylactic vaccine for those who have not developed. At present, hopes of achieving a complete HIV cure whereby all HIV positive cells are eradicated from the system of an infected individual receiving HAART is somewhat remote. It is time for all to learn more and more about the HIV disease and the advances in the field of its research. Reference Portal on HIV reservoirs & Eradication Strategies is a website that talks about their commitment in finding out HIV cure and HIV eradication. You are advised to visit the website to increase your knowledge on HIV/AIDS.

Company name: AVPS
Company phone number: +33-4-94616340
URL/Domain: http://www.hiv-reservoir.net

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