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Ciprofloxacin belongs to a group of antibiotic medicines called quinolones (pronounced KWIN-a-lones). Quinolones works by killing the
bacteria which cause different bacterial infections. It’s not work against viral infections such as colds or flu because the cause of this illnes may be viruses they are resistant to Ciprofloxacin. The fluoroquinolones they are generally not recommended for use in treating infections caused buy many anaerobic bacteria because of weak activity and variable activity against most streptococci, if these types of microbes are present. Ciprofloxacin’s action is by inhibiting bacterial DNA-gyrase which prevents DNA supercoiling and DNA synthesis. Ciprofloxacin, is a concentration of dependent bactericidal agent, it is a second-generation fluoroquinolone . This antimicrobial drug has shown activity against some Gram-positive aerobes such as staphylococci, and a wide range of Gram-negative bacilli and cocci, which include: pasteurella spp., klebsiella spp., , salmonella, pseudomonas spp., mycoplasma, and chlamydia and other organisms
It is well absorbed when is taken orally, and the presence of food in the stomach may delay it does not effect its absorption capability, Generic Ciprofloxacin tablets are taken on an empty stomach 2 hours after meals. Ciprofloxacin can be found in small concentrations in the cerebral spinal fluid and are well distributed throughout the body. Ciprofloxacin is a metabolite of enrofloxacin, and like enrofloxacin is eliminated by both renal and hepatic mechanisms, as well as in breast milk.
Like all medications and drugs Ciprofloxacin has side effects, the most frequent side effects are: Nausea, diarrhoea, vomiting, and abdominal pain, bad taste in the mouth, restlessness, rash, sensitivity to sunlight and seizures are other.
Do not take Ciprofloxacin if you have epilepsy or kidney disease, or if you are pregnant, or want to become pregnant, or are breastfeeding, notify your doctor before you start taking this medicine. if you have had an allergic reaction to ciprofloxacin or other quinolone medicines such as norfloxacin (Noroxin) do not take it
Ciprofloxacin may have drug interactions with: Iron, zinc, calcium, magnesium, aluminum, corticosteroids (increase risk of tendon rupture), antacids, electrolyte supplements, quinapril, sucralfate, certain antiarrhythmics, didanosine formulations (chewable/buffered tablets and pediatric powder for oral suspension), theophyllines, antacids, cyclosporine, cimetidine. Avoid driving or using machinery until you know how it will affect you and this drug may make you dizzy or lightheaded.

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