Go to countrydise to lessen the risk of Allergies

Imagine being allergic to something that your own body produces which is physiologically crucial for your health and well-being! I mean, it does make sense that your immune defenses go on a paranoid shooting spree when a foreign substance that it does not understand enters the body such as an external allergen (food, pollens, paint, drugs, alcohol, dust, metals…… the list goes on!). However, logic goes out of the window and a rational reason is hard to come by to explain how a person’s immune system can be allergic to a biological enzyme that is produced in a normal physiological process that is necessary for the body and is an essential part of that person’s biological sexuality! It sounds sick!

The study which was published in the February 2012 edition of the Pediatric Allergy and Immunology Journal, found that growing up on a farm results in immune system alterations that reduces an individual’s risk for developing allergies and allergic reactions. The study was conducted on piglets because they contain many of the same genetics, immunity functions, metabolic mechanisms and physiological aspects as humans. There were two sets of piglets; the first of which was nursed by their mothers and reared on a farm. Their siblings on the other hand, were fed formula milk and spent their early life in an extremely hygienic isolator unit, in order to mirror the sterile lifestyle and environment that human babies are most often raised in.

According to the study, the piglets raised on the farm demonstrated a reduced antibody response to novel food proteins when they were weaned. In other words, they were less likely to experience allergic reactions to a common food allergen. The researchers concluded that early-life exposure to certain environmental components of farms, positively impacts regulatory mechanisms of the immune system and thereby helps to reduce the risk for developing allergies.

A type of T cell that provides help to other cells in theimmune response by recognizing foreign antigens and secreting substances called cytokines that activate T and B cells. T-helper cells fall into two main classes: those that activate other T cells to achieve cellular inflammatory responses; and those that drive B cells to produce antibodies in the humoralimmune response. These two classes of response are generally incompatible with one another and require coordination by substances called cytokines to promote one response while dampening the other.

More research needs to be done in order to determine the exact way in which farm living works as a preventative measure against the development of allergies. Previous research has found that intestinal bacteria (acquired in infancy) play a pivotal role in the development of a healthy immune system and perhaps the farm environment allowed for a greater flourishing of the beneficial bacteria. The researchers at Bristol’s School of Veterinary Science speculates that factors such as aerial contaminants, antigens from bedding, social and maternal interactions and early nutrition may also have played a preventative role in the development of allergies in the farm raised piglets.

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